![]() Can Zyrtec keep you awake?īoth Zyrtec and Claritin may make you drowsy or tired. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Can Zyrtec D cause insomnia?ĭrowsiness, dizziness, tiredness, dry mouth, nausea, headache, or trouble sleeping may occur. The antihistamine (Cetirizine) in Zyrtec D (Cetirizine / Pseudoephedrine) causes less drowsiness than other medications like Benadryl. It can keep you up at night if you take it too close to bedtime. Zyrtec D (Cetirizine / Pseudoephedrine) relieves allergies and congestion without causing daytime sleepiness.
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